When is blood glucose used for exercise energy?
Is blood glucose primarily used in the aerobic pathway (Krebs cycle), or is it also used in the anaerobic pathway when muscle glycogen stores are depleted during exercise? Thanks!
Isn’t glucose and glycogen formed from carbohydrates?
Thanks Travis! Am I correct in saying that muscle glycogen is used for anaerobic needs and blood glucose is used for aerobic fuel then?
Apparently Tristannnnn’s "A" didn’t require her to know that glucose IS a carbohydrate, and is the primary energy source for all cells. However, she is correct, that glycogen is actually stored glucose in the liver, which can be broken down to glucose again for times of low energy. Lactate removes hydrogens from NADH to convert them to NAD in order to provide plenty of available NAD to prevent metabolism from grinding to a halt. This is what causes the lactic acid build sensation once it’s excreted from the cells.
The increase in breathing is actually a response to an increase in carbon waste buildup in the blood. It promotes more breaths to intake more oxygen which is inevitably needed as the last electron donor at the end of metabolism.
Glucose is primarily used in aerobic conditions. It will continue to use glucose until the glycogen reserves are depleted, and will then move on to lipid molecules and eventually amino acids for sources of energy.
2 responses so far

anaerobic pathway.
aerobic is when it starts breaking down bigger energy particles like carbohydrate.
but for the record, glycogen is made up of glucose.
about 1,700-600,000 unit of glucose makes up for one glycogen. i read that somewhere.
so when glycogen depletes (long after single particle glucose depleted), you body turns to aerobic exercise. thats when you start burning Carbohydrate, and thats when you need to breathe in more air.
this leads to lactic acid build up, which will cause the burning sensation midway through a hard workout. also, my running coach told me the same thing.
References :
A in AP bio last year.
Apparently Tristannnnn’s "A" didn’t require her to know that glucose IS a carbohydrate, and is the primary energy source for all cells. However, she is correct, that glycogen is actually stored glucose in the liver, which can be broken down to glucose again for times of low energy. Lactate removes hydrogens from NADH to convert them to NAD in order to provide plenty of available NAD to prevent metabolism from grinding to a halt. This is what causes the lactic acid build sensation once it’s excreted from the cells.
The increase in breathing is actually a response to an increase in carbon waste buildup in the blood. It promotes more breaths to intake more oxygen which is inevitably needed as the last electron donor at the end of metabolism.
Glucose is primarily used in aerobic conditions. It will continue to use glucose until the glycogen reserves are depleted, and will then move on to lipid molecules and eventually amino acids for sources of energy.
References :
BS in Biology and Biochemistry
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